Thermo Fisher Scientific Human Parkin (aa 298-313) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

purified

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-159 is a 15 amino acid synthetic peptide whose sequence is from human parkin. The sequence of this peptide is (amino to carboxy terminus): C- I (298)-K-E-L-H-H-F-R-I-L- G-E-E-Q-Y-N (313)

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human parkin, catalog # PA1-751. Using a solution with equal weights per unit volume of peptide and corresponding antibody will yield a solution with a large molar excess of peptide that is able to competitively bind the antibody.

Reconstitute with 0.1 mL of distilled water.

Target Information

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.