Thermo Fisher Scientific Aquaporin 5 Polyclonal Antibody, FITC
Aquaporin 5 단백질을 인식하는 FITC 표지 폴리클로날 항체로, Western blot, IHC, ELISA, IP에 사용 가능. 다양한 종(Bovine, Human, Mouse 등)에 반응하며, 고순도의 친화 크로마토그래피 정제. 연구용으로 폐수, 조직, 세포 내 수분 이동 연구에 적합.
- 카탈로그번호
- AQP5-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Sheep, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 250–299 on rat Aquaporin 5 protein |
| Conjugate | FITC (Fluorescein isothiocyanate) |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9, and one of the two AQP10 transcripts are also permeable to urea and glycerol.
AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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