Thermo Fisher Scientific Aquaporin 4 Polyclonal Antibody, FITC
FITC로 표지된 Aquaporin 4 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용 가능. 토끼 IgG 항체로 인간, 마우스, 랫 등 반응. 합성 펩타이드 항원 사용, 친화 크로마토그래피 정제. -20°C 암소 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Sheep, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 300–323 on rat Aquaporin 4 protein |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In skeletal muscle, AQP4 (aquaporin 4, also known as mercurial insensitive water channel) localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins facilitating water movement across cell membranes. This function is conserved across animals, plants, and bacteria. Multiple isoforms (AQP0–AQP10) exist in mammals, often co-expressed within the same cell. While most AQPs are selective for water, AQP3, AQP7, AQP9, and one AQP10 transcript also transport urea and glycerol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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