Thermo Fisher Scientific YPEL4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunocytochemistry (ICC/IF)

25 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A 12 amino acid synthetic peptide near the amino terminus of human YPEL4 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:YPEL4,uniProtId:Q96NS1-1,ncbiNodeId:9606,antigenRange:1,antigenLength:127,antigenImageFileName:PA5-34350_YPEL4_Q96NS1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-34350_YPEL4_Q96NS1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2551702

Product Specific Information

A suggested positive control is SW480 cell lysate.

PA5-34350 can be used with blocking peptide PEP-1393.

Target Information

YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP). It has been suggested that MVP can inhibit YPEL4`s ability to activate Elk-1 in the MAPK signaling pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.