Thermo Fisher Scientific GPR77 Polyclonal Antibody
Rabbit polyclonal antibody targeting GPR77 for research use. Validated in Western blot with dilution range 1:500–1:3,000. Supplied as unconjugated liquid at 1 mg/mL concentration. Recommended positive controls include 293T, HeLa, and Raji cells.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 248–337 of GPR77 (Uniprot ID: Q9P296) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154200 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, Molt-4, Raji
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
C5AR2 is an orphan member of the anaphylatoxin receptor family. It is a seven-transmembrane G-protein-coupled receptor with an N-terminal N-glycosylation site, conserved cysteines, and potential C-terminal phosphorylation sites.
It binds to C5a and C5a-des-Arg, serving as a regulated scavenger receptor that negatively modulates C5aR-mediated inflammation.
Northern blot analysis indicates co-expression with C5aR in tissues and cells including neutrophils, macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary, and testis.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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