
Thermo Fisher Scientific Ku (p70/p80) (Nuclear Marker) Monoclonal Antibody (KU729)
Ku70/Ku80 핵심 핵 마커 단백질을 인식하는 Mouse monoclonal antibody로, ICC/IF 및 Flow Cytometry에 최적화됨. Human 및 비인간 영장류 반응성. Unconjugated 형태, Protein A/G 정제, PBS 버퍼에 보존. 연구용 DNA 복구 및 핵 단백질 검출에 적합.
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Thermo Fisher Scientific Ku (p70/p80) (Nuclear Marker) Monoclonal Antibody (KU729)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KU729 |
| Immunogen | Nuclear extract of human HL-60 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
- Does not react with Mouse, Rat, Chicken
Target Information
The Ku protein is a heterodimer composed of 70 kDa and 80 kDa subunits (Ku70/Ku80), also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5.
Ku acts as the DNA-binding component of the DNA-dependent protein kinase complex and participates in DNA double-strand break repair via non-homologous end joining and V(D)J recombination.
Defects in this gene can lead to impaired DNA repair and altered radiosensitivity.
[RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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