Thermo Fisher Scientific Ku (p70/p80) (Nuclear Marker) Monoclonal Antibody (KU729), CF 488
Ku 단백질(p70/p80)을 인식하는 핵 마커용 단클론 항체로, CF 488 형광 표지. 인간 및 비인간 영장류 반응성. ICC/IF 및 유세포분석에 적합. 단백질 A/G 정제, 액상 형태, 4°C 보관.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
Flow Cytometry (Flow)
- Tested Dilution: 5 µL/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KU729 |
| Immunogen | Nuclear extract of human HL-60 cells |
| Conjugate | CF® 488 |
| Excitation / Emission Max | 488 / 515 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
- Does not react with Mouse, Rat, or Chicken.
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5.
Ku is the DNA-binding component of the DNA-dependent protein kinase and functions with the DNA ligase IV–XRCC4 complex in DNA double-strand break repair via non-homologous end joining and V(D)J recombination.
This gene complements the Chinese hamster xrs-6 mutant defective in DNA repair and recombination.
A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
[Provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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