Thermo Fisher Scientific Ku (p70/p80) (Nuclear Marker) Monoclonal Antibody (KU729), PE

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

1:50-1:100

-

Flow Cytometry (Flow)

5 µL/10^6 cells

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

KU729

Immunogen

Nuclear extract of human HL-60 cells if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ku70/Ku80,uniProtId:P12956-1,ncbiNodeId:9606,antigenRange:1-609,antigenLength:609,antigenImageFileName:2547-MSM1-PE-100T_Ku70Ku80_P12956-1_House_mouse.svg,antigenImageFileNamePDP:2547-MSM1-PE-100T_Ku70Ku80_P12956-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:Ku70/Ku80,uniProtId:P13010-1,ncbiNodeId:9606,antigenRange:1-732,antigenLength:732,antigenImageFileName:2547-MSM1-PE-100T_Ku70Ku80_P13010-1_House_mouse.svg,antigenImageFileNamePDP:2547-MSM1-PE-100T_Ku70Ku80_P13010-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

PE PE PE

View additional formats

• Unconjugated
• CF 488
• Request custom conjugation

Excitation/Emission Max

565/576 nm View spectra

Form

Liquid

Concentration

100 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C, store in dark, DO NOT FREEZE!

Shipping conditions

Wet ice

Product Specific Information

Does not react with Mouse, Rat or Chicken

Target Information

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.