Thermo Fisher Scientific SEMA3A Recombinant Rabbit Monoclonal Antibody (7M10D0)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000-1:20,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7M10D0

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 582-771 of human Semaphorin 3A (NP_006071.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SEMA3A,uniProtId:Q14563-1,ncbiNodeId:9606,antigenRange:582-771,antigenLength:771,antigenImageFileName:MA5-51333_SEMA3A_Q14563-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51333_SEMA3A_Q14563-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.055 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3093894

Product Specific Information

Immunogen sequence: ERIIYGVENS STFLECSPKS QRALVYWQFQ RRNEERKEEI RVDDHIIRTD QGLLLRSLQQ KDSGNYLCHA VEHGFIQTLL KVTLEVIDTE HLEELLHKDD DGDGSKTKEM SNSMTPSQKV WYRDFMQLIN HPNLNTMDEF CEQVWKRDRK QRRQRPGHTP GNSNKWKHLQ ENKKGRNRRT HEFERAPRSV

Target Information

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer`s disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.