Thermo Fisher Scientific IL-2 Recombinant Rabbit Monoclonal Antibody (2L3B5)
Recombinant Rabbit Monoclonal Antibody로 Mouse IL-2를 특이적으로 인식. Western blot과 ELISA에 적합하며 높은 특이성과 재현성을 제공. HEK293 발현 시스템에서 생산되어 일관된 품질 보장. 연구용으로 면역반응 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2L3B5 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–169 of mouse IL2 (NP_032392.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093100 |
Product Specific Information
Immunogen sequence:
APTSSSTSSS TAEAQQQQQQ QQQQQQHLEQ LLMDLQELLS RMENYRNLKL PRMLTFKFYL PKQATELKDL QCLEDELGPL RHVLDLTQSK SFQLEDAENF ISNIRVTVVK LKGSDNTFEC QFDDESATVV DFLRRWIAFC QSIISTSPQ
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7. The IL-2 gene expression in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression control. Gene disruption of IL-2 in mice leads to ulcerative colitis-like disease, indicating its essential role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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