Thermo Fisher Scientific CRSP130 Polyclonal Antibody
CRSP130 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화됨. 인간 단백질에 반응하며 Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관, -20°C에서 안정적 저장 가능. 연구용으로만 사용.
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Thermo Fisher Scientific CRSP130 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MED23 (Accession Q9ULK4), corresponding to amino acid residues Q6–H56 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818545 |
Product Specific Information
Antibody detects endogenous levels of total CRSP130.
Target Information
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex consisting of nine distinct subunits. Several members of the CRSP family share sequence similarity with yeast transcriptional mediator proteins, including CRSP150 (related to yeast Rgr1) and CRSP70 (similar to elongation factor TFIIS). CRSP77 and CRSP150 are related to proteins within the murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins.
CRSP subunits also associate with larger multimeric co-activator complexes such as ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and NAT, a polymerase II-interacting complex that represses activated transcription.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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