Thermo Fisher Scientific Cdc27 Recombinant Rabbit Monoclonal Antibody (SD85-02)
Thermo Fisher의 Cdc27 재조합 토끼 단클론 항체(SD85-02)는 인간, 마우스, 랫트 시료에 반응하며 Western blot에 적합합니다. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션으로 안정적입니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- MA532414
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cdc27 Recombinant Rabbit Monoclonal Antibody (SD85-02)
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD85-02 |
| Immunogen | Recombinant protein within Human Cdc27 aa 662–824 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809692 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The Cdc27 protein shares strong similarity with Saccharomyces cerevisiae Cdc27 and Schizosaccharomyces pombe nuc2. It is a component of the anaphase-promoting complex (APC), composed of eight conserved subunits in eukaryotic cells.
APC catalyzes the formation of cyclin B–ubiquitin conjugates, mediating ubiquitin-dependent proteolysis of B-type cyclins.
Cdc27 contains TPR (tetratricopeptide repeat) domains important for protein-protein interactions and interacts with mitotic checkpoint proteins such as Mad2, p55CDC, and BUBR1, implicating its role in mitotic timing control.
Alternative splicing generates multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.