Thermo Fisher Scientific ARF1 Recombinant Rabbit Monoclonal Antibody (SD2002)
ARF1 단백질을 표적으로 하는 Thermo Fisher의 재조합 토끼 단클론 항체로, 높은 특이성과 민감도를 제공. WB, IHC, Flow Cytometry 등 다양한 응용 가능. HEK293 세포에서 발현된 IgG 형 항체로, 일관된 로트 간 품질 보장. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SD2002 |
| Immunogen | Synthetic peptide within Human ARF1 aa 61–110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809627 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family, encoding small guanine nucleotide-binding proteins that stimulate ADP-ribosyltransferase activity of cholera toxin. ARF proteins play a role in vesicular trafficking as activators of phospholipase D.
The ARF family includes 6 ARF proteins and 11 ARF-like proteins, belonging to the RAS superfamily.
ARF proteins are categorized as:
- Class I: ARF1, ARF2, ARF3
- Class II: ARF4, ARF5
- Class III: ARF6
ARF1 is localized to the Golgi apparatus and plays a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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