Thermo Fisher Scientific CD94 Monoclonal Antibody (DX22), PE, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 5 µL (0.125 µg)/test

Product Specifications

Additional Formats

• Alexa Fluor 647
• APC
• FITC
• Request custom conjugation

Product Specific Information

The DX22 monoclonal antibody reacts with human CD94, a 70 kDa type II transmembrane glycoprotein belonging to the C-type lectin superfamily. CD94 forms heterodimers with NKG2 on the cell surface and is expressed by NK cells, a subset of γδ T cells, and NKT cells. It plays a key role in adhesion and activation of NK cell lineage.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells
• Recommended Usage: 5 µL (0.125 µg) per test (100 µL final volume; 10⁵–10⁸ cells/test)
• Excitation: 488–561 nm
• Emission: 578 nm
• Compatible Lasers: Blue, Green, Yellow-Green
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

Natural killer (NK) cells are a distinct lineage of lymphocytes mediating cytotoxic activity and cytokine secretion upon immune stimulation. Several C-type lectin superfamily genes, including NKG2 family members, are expressed by NK cells and may regulate NK cell function.
KLRD1 (CD94) is preferentially expressed on NK cells and is a type II membrane protein with an external C terminus. Three transcript variants encoding two isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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