Thermo Fisher Scientific ZCCHC9 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:25–1:100

Product Specifications

Product Specific Information

The antibody detects endogenous levels of total ZCCHC9 protein.

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass transcriptional activation or repression.
ZCCHC9 (zinc finger, CCHC domain containing 9) is a 271 amino acid protein that contains four CCHC-type zinc fingers, suggesting a role in transcriptional regulation.
The gene encoding ZCCHC9 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome.
Chromosome 5 is associated with several genetic disorders, including:

• Cockayne syndrome (ERCC8 gene)
• Familial adenomatous polyposis (APC tumor suppressor gene)
• Treacher Collins syndrome (TCOF1 gene)
• Cri du chat syndrome (deletion of p arm)
• Therapy-related acute myelogenous leukemias and myelodysplastic syndrome (deletion of q arm)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.