Thermo Fisher Scientific HMGN3 Polyclonal Antibody
HMGN3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간과 생쥐 시료에 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체로, PBS/glycerol buffer에 보관.
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Thermo Fisher Scientific HMGN3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:25–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human HMGN3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636631 |
Product Specific Information
This antibody detects endogenous levels of total HMGN3 protein.
Target Information
HMGN3 binds to nucleosomes and regulates chromatin structure and chromatin-dependent processes such as transcription, DNA replication, and DNA repair. It influences insulin and glucagon levels and modulates pancreatic gene expression related to insulin secretion.
It also regulates the glucose transporter SLC2A2 by binding to its promoter region and recruiting transcription factors including PDX1.
Additionally, it controls SLC6A9 expression, affecting glycine concentration in synaptic junctions within the CNS.
HMGN3 may also play a role in ocular development and astrocyte function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-51183_HMGN3_Q15651-1_Rabbit.svg, PA5-51183_HMGN3_Q15651-1_Rabbit_PDP.jpeg)
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