Thermo Fisher Scientific Myeloperoxidase Monoclonal Antibody (A1F4)
Myeloperoxidase 단백질을 인식하는 Mouse monoclonal antibody (Clone A1F4). Western blot, IHC(P), Flow cytometry에 사용 가능. Human 시료 반응성. Protein G로 정제된 액상 항체로, 4°C 또는 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1F4 |
| Immunogen | Recombinant protein within human Myeloperoxidase aa 550–745 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911538 |
Product Specific Information
- Positive Control: HL-60 cells, human tonsil tissue, human colon tissue, human colon carcinoma tissue
- Subcellular Location: Lysosome
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and cleaved into light and heavy chains. The mature MPO is a tetramer composed of two light and two heavy chains. This enzyme produces hypohalous acids crucial for the microbicidal activity of neutrophils.
Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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