Thermo Fisher Scientific Cytokeratin 17 Monoclonal Antibody (A2B9)
Cytokeratin 17 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Human 시료에 반응합니다. Western blot, IHC(P), Flow cytometry 등에 사용 가능하며, Protein G로 정제된 액상 형태입니다. 세포 내 위치 확인 및 상피세포 종양 구분 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A2B9 |
| Immunogen | Synthetic peptide within Human Cytokeratin 17 (aa 383–432) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911539 |
Product Specific Information
- Positive Control: SiHa cell lysate, human tonsil tissue, human liver carcinoma tissue, human skin tissue
- Subcellular Location: Cytoplasm
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented by at least 20 different polypeptides in human epithelial tissues. They have molecular weights ranging from approximately 40 kDa to 68 kDa and isoelectric points between pH 4.9–7.8.
Each cytokeratin subtype is associated with specific epithelial types and differentiation stages. Cytokeratin expression patterns are widely used to distinguish epithelial malignancies. Cytokeratin antibodies assist in tumor differential diagnosis via immunohistochemistry and are also valuable in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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