Thermo Fisher Scientific TGFBI Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_0003491) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TGFBI,uniProtId:Q15582-1,ncbiNodeId:9606,antigenRange:550-650,antigenLength:683,antigenImageFileName:PA5-88096_TGFBI_Q15582-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88096_TGFBI_Q15582-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.66 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804648

Product Specific Information

Positive Samples: BxPC-3, Mouse heart, Mouse kidney, Rat kidney; Cellular Location: extracellular matrix, extracellular space

Immunogen sequence: LPPRERSRLL GDAKELANIL KYHIGDEILV SGGIGALVRL KSLQGDKLEV SLKNNVVSVN KEPVAEPDIM ATNGVVHVIT NVLQPPANRP QERGDELADS A

Target Information

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.