Thermo Fisher Scientific MLLT11 Polyclonal Antibody
Human MLLT11 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:100–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 용액 형태로 제공. 내인성 MLLT11/AF1Q 단백질 검출에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MLLT11 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length fusion protein of human MLLT11 (UniProt ID: Q13015-1, amino acids 1–90) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636632 |
Product Specific Information
This antibody detects endogenous levels of total MLLT11 / AF1Q protein.
Target Information
The MLLT11 gene (also known as ALL1, HRX, or MLL) located on chromosome 11q23 is known to fuse with various translocation partners in leukemia cases. Translocations such as t(1;11)(q21;q23) result in fusion of the MLL gene with a gene on 1q21, observed in infants with acute myelomonocytic leukemia. The N-terminal portion of the MLL gene is critical for leukemogenesis in such translocations.
This gene encodes a 90-amino-acid protein that is highly expressed in the thymus but not in peripheral lymphoid tissues. Unlike its restricted expression in normal hematopoietic tissue, it is expressed in all leukemic cell lines tested.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.