Thermo Fisher Scientific IL10RA Polyclonal Antibody
IL10RA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 액상 형태로 1 mg/mL 농도입니다. Affinity chromatography로 정제되었으며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IL10RA (Accession Q13651), corresponding to amino acid residues G472–E522 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900036 |
Product Specific Information
This antibody detects endogenous levels of total IL-10R alpha.
Target Information
The protein encoded by this gene is a receptor for interleukin 10. It is structurally related to interferon receptors and mediates the immunosuppressive signal of interleukin 10, inhibiting synthesis of proinflammatory cytokines. This receptor promotes survival of progenitor myeloid cells via the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants have been identified: one protein-coding and one non-coding.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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