Thermo Fisher Scientific Heavy chain of IgG4 Polyclonal Antibody
인간, 마우스, 랫트의 IgG4 중쇄를 인식하는 폴리클로날 항체. Western blot에 적합하며, 친화 크로마토그래피로 정제됨. PBS/50% 글리세롤 용액 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IGHG4 (Accession P01861), corresponding to amino acid residues K88–E138 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900034 |
Product Specific Information
Antibody detects endogenous levels of total IgG4.
Target Information
The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains.
With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions.
These regions also function to hold the variable regions together by using the disulfide bond between them.
The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms.
Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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