Thermo Fisher Scientific GluR1 Monoclonal Antibody (N355/1), APC
GluR1 단백질을 인식하는 마우스 단클론 항체로, APC 형광 표지되어 있습니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간, 생쥐, 랫트 반응성을 보입니다. 단백질 G로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N355/1 |
| Immunogen | Fusion protein amino acids 1–389 (extracellular N-terminus) of rat GluA1/GluR1 |
| Conjugate | APC |
| Excitation/Emission Max | 651/660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932081 |
Available Formats
- Unconjugated (MA5-27694)
- FITC (MA5-45628)
- PE (MA5-45630)
- PerCP (MA5-45629)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45627 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 100 kDa.
- Does not cross-react with GluR2.
- This antibody was formerly sold as clone S355-1.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal into an electrical impulse. The receptor then rapidly desensitizes and enters a transient inactive state. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed accumulation of current flux upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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