Thermo Fisher Scientific RAB27A Polyclonal Antibody
RAB27A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 검증됨. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 단백질 수송 및 GTPase 신호전달 연구에 적합. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RAB27A. Recombinant protein control fragment (Product # RP-95382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646229 |
Product Specific Information
Immunogen sequence:
LQLWDTAGQE RFRSLTTAFF RDAMGFLLLF DLTNEQSFLN VRNWISQLQM HAYCENPDIV LCGNKSDLED QRVVKEEEAI ALAEKYGIPY FETSAANGTN ISQAIEMLLD LIMKRMERCV DKSWIPEGVV RSNGHASTDQ LS
Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 97%
Target Information
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase-mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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