Thermo Fisher Scientific EDDM3B Polyclonal Antibody
Human EDDM3B 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000~1:2,500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS와 글리세롤 완충액에 보관. 연구용으로 적합하며 장기 보관 시 -20°C 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human EDDM3B. Recombinant protein control fragment (Product #RP-88881). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640887 |
Product Specific Information
Immunogen sequence:
EVSWREFMKQ HYLSPSREFR EYKCDVLMRE NEALKDKSSH MFIYISWYKI EHICTSDNWM DRFRNAYVWV QNPLKVLKCH QENSKNSYTE SRSFNYIEFH CSMDGYVDSI EDLKMVEPIG N
- Highest antigen sequence identity to the following orthologs:
- Mouse: 56%
- Rat: 58%
Target Information
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components, and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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