Thermo Fisher Scientific EDDM3B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EDDM3B. Recombinant protein control fragment (Product #RP-88881). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EDDM3B,uniProtId:P56851-1,ncbiNodeId:9606,antigenRange:27-147,antigenLength:147,antigenImageFileName:PA5-51559_EDDM3B_P56851-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51559_EDDM3B_P56851-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640887

Product Specific Information

Immunogen sequence: EVSWREFMKQ HYLSPSREFR EYKCDVLMRE NEALKDKSSH MFIYISWYKI EHICTSDNWM DRFRNAYVWV QNPLKVLKCH QENSKNSYTE SRSFNYIEFH CSMDGYVDSI EDLKMVEPIG N

Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 58%.

Target Information

Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.