Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI1G2), TrueMAB
Human GORAB 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P)에서 검증됨. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–394 of human GORAB produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. This complex consists of elongins A/A2, B, and C, and functions to activate elongation by RNA polymerase II by suppressing transient pausing within transcription units.
Elongin A serves as the transcriptionally active component, while elongins B and C act as regulatory subunits. Elongin A2 is specifically expressed in the testis and can form a stable complex with elongins B and C.
The von Hippel–Lindau tumor suppressor protein binds to elongins B and C, thereby inhibiting transcription elongation. Western blots using two different antibodies against unique regions of this protein confirm consistent apparent molecular weight results.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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