Thermo Fisher Scientific SCYL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SCYL1. Recombinant protein control fragment (Product #RP-91451). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SCYL1,uniProtId:Q96KG9-1,ncbiNodeId:9606,antigenRange:303-430,antigenLength:808,antigenImageFileName:PA5-53267_SCYL1_Q96KG9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53267_SCYL1_Q96KG9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647042

Product Specific Information

Immunogen sequence: AFPEDFCRHK VLPQLLTAFE FGNAGAVVLT PLFKVGKFLS AEEYQQKIIP VVVKMFSSTD RAMRIRLLQQ MEQFIQYLDE PTVNTQIFPH VVHGFLDTNP AIREQTVKSM LLLAPKLNEA NLNVELMK

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.

Target Information

With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms` tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.