Thermo Fisher Scientific SCYL1 Polyclonal Antibody
SCYL1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간 시료에 반응합니다. ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 0.2 mg/mL 농도의 액상 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCYL1. Recombinant protein control fragment (Product # RP-91451) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647042 |
Product Specific Information
Immunogen sequence:
AFPEDFCRHK VLPQLLTAFE FGNAGAVVLT PLFKVGKFLS AEEYQQKIIP VVVKMFSSTD
RAMRIRLLQQ MEQFIQYLDE PTVNTQIFPH VVHGFLDTNP AIREQTVKSM LLLAPKLNEA NLNVELMK
Sequence identity with orthologs:
- Mouse: 96%
- Rat: 95%
Target Information
Chromosome 11 contains approximately 135 million base pairs and around 1,400 genes, representing about 4% of human genomic DNA. It is considered gene- and disease-association dense. The Atm gene on chromosome 11 is critical for regulating cell cycle arrest and apoptosis following double-strand DNA breaks. Mutations in Atm cause ataxia-telangiectasia.
Other notable genes include:
- HBB: mutations cause Sickle cell anemia and β-thalassemia
- WT1: mutations associated with Wilms’ tumor, WAGR syndrome, and Denys-Drash syndrome
- Additional disorders linked to chromosome 11 include Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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