Thermo Fisher Scientific RSF1 Monoclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Immunogen

Recombinant human RSF1 (remodeling and spacing factor 1) protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2605888

Target Information

RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.