Thermo Fisher Scientific H3K4me1 Monoclonal Antibody
H3K4me1 단일클론 항체로 인간 히스톤 H3의 Lys4 단일메틸화를 특이적으로 인식. Western blot, ICC/IF, peptide ELISA에 사용 가능. 단백질 A로 정제된 액상 항체로 안정적인 신호 검출 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:500 |
| Peptide-ELISA (pep-ELISA) | 1:5,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to human histone H3, monomethylated at lysine 4 (H3K4me1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| RRID | AB_2608306 |
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways to change chromatin structure or enable transcription factor binding. The N-terminal tail of histone H3 can undergo methylation, acetylation, and phosphorylation, influencing multiple cellular processes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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