Thermo Fisher Scientific NAE1 Monoclonal Antibody (OTI1E9), TrueMAB
NAE1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot에 최적화되어 있습니다. Human 시료에 반응하며, carrier-free 형태로 제공되어 결합 실험에 적합합니다. 동결건조 상태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–274 of human NAE1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NAE1 gene encodes a protein that binds to the beta-amyloid precursor protein, which is involved in signal transduction and may play a role in Alzheimer’s disease pathogenesis.
NAE1 forms a heterodimer with UBE1C to bind and activate NEDD8, a ubiquitin-like protein essential for cell cycle progression through the S/M checkpoint.
Three transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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