Thermo Fisher Scientific Sortilin (extracellular) Polyclonal Antibody
Sortilin 단백질의 세포외 도메인을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. 연구용으로만 사용.
- 카탈로그번호
- ANT-009-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Sortilin (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:400 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DKDTTRRIHVSTDQD(C) corresponding to amino acid residues 320–335 of human Sortilin, extracellular domain |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature and should be stored at -20°C upon arrival.
Reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and store at -20°C. Avoid multiple freeze/thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g for 5 min).
Target Information
Sortilin functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface.
It is required for protein transport from the Golgi apparatus to lysosomes and endosomes, independent of the mannose-6-phosphate receptor (M6PR).
Sortilin promotes neuronal apoptosis by mediating endocytosis of proBDNF and proNGFB, and also acts as a receptor for neurotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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