
Thermo Fisher Scientific p75 NGF Receptor (intracellular) Polyclonal Antibody
p75 NGF 수용체의 세포내 도메인을 인식하는 Rabbit Polyclonal 항체. Western blot 및 동결절편 면역조직화학에 적합. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피 정제 및 동결건조 형태로 제공. 신경세포 발달 및 NGFR 연구용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CKQNKQGANSRPVNQT corresponding to amino acid residues 278–293 of human p75NTR (intracellular, juxta membrane domain) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
- Reconstituted solution: store at 4°C, protected from light, up to 1 week.
- For long-term storage, aliquot and keep at -20°C. Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Neurotrophic factors regulate the survival, differentiation, and maintenance of neurons in both peripheral and central nervous systems, as well as other neural crest-derived cells. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are valuable tools for detecting and characterizing NGFR p75, aiding research into neuronal development, plasticity, and repair mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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