Thermo Fisher Scientific E2F1 Polyclonal Antibody
E2F1 전사 인자에 대한 Rabbit Polyclonal Antibody로, Western Blot 및 Immunoprecipitation에 적합. 인간 E2F1의 387–437번 잔기 영역을 면역원으로 사용. 1 mg/mL 농도의 액상 형태, 4°C 보관. Mouse와 교차 반응 예측됨.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific E2F1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,500–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 387 and 437 of human E2F Transcription Factor 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of the cell cycle and the action of tumor suppressor proteins. It is also a target of transforming proteins of small DNA tumor viruses.
E2F proteins contain conserved domains including:
- DNA binding domain
- Dimerization domain (interacts with DP proteins)
- Transactivation domain (enriched in acidic amino acids)
- Tumor suppressor protein association domain (within transactivation domain)
E2F1, along with E2F2 and E2F3, has an additional cyclin-binding domain. It binds preferentially to retinoblastoma protein (pRB) in a cell-cycle dependent manner and can mediate both cell proliferation and p53-dependent/independent apoptosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.