Thermo Fisher Scientific FXIIIA Polyclonal Antibody, FITC
Factor XIII A 단위를 인식하는 FITC 결합 폴리클로날 항체로, WB, ELISA, IP에 적합합니다. 고순도의 친화 크로마토그래피 정제 제품이며, 다양한 종(Cat, Human, Mouse, Non-human primate)에 반응합니다. 연구용으로 -20°C 암소 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cat, Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 700–732 of human factor XIII A subunit protein |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the coagulation factor XIII A subunit, the final zymogen activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of two A subunits (catalytic) and two B subunits (non-enzymatic carriers). Platelet factor XIII consists of two A subunits identical to those in plasma. Upon activation by thrombin and calcium, the enzyme factor XIIIa catalyzes crosslinking between fibrin molecules, stabilizing the clot, and also crosslinks α2-plasmin inhibitor or fibronectin to fibrin α chains. Deficiency in factor XIII can cause bleeding disorders, poor wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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