Thermo Fisher Scientific BCL11A Recombinant Rabbit Monoclonal Antibody (JB35-68)
BCL11A 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot, IHC, ICC/IF, Flow cytometry에 적합하며, 높은 특이성과 재현성을 제공합니다. 단백질 A로 정제된 액상 항체로 연구용에 최적화되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | 1:1,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JB35-68 |
| Immunogen | Recombinant protein within Human Ctip1 (aa 381–609) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2848586 |
Product Specific Information
Positive Control: Daudi, U937, human tonsil tissue, mouse cerebellum tissue, Jurkat.
Target Information
This gene encodes a C2H2 type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis, as translocations associated with B-cell malignancies also deregulate its expression. Multiple transcript variants encoding several isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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