Thermo Fisher Scientific Troponin T Monoclonal Antibody (9B1)
Human cardiac Troponin T 인식 단일클론 항체로 Western blot 및 IHC(Paraffin) 적용 가능. Mouse IgG1 형식이며 Protein A로 정제된 액상 형태. 심근 및 골격근 양성 대조군에 적합하며 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9B1 |
| Immunogen | Highly purified human cardiac troponin T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human cardiac or skeletal muscle
- Cellular location: Myofibrils T bands
Target Information
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, located on the thin filament of striated muscles. It regulates muscle contraction in response to intracellular calcium ion concentration changes. Cardiac Troponin T plays a key role in muscle function and myofibril formation. In humans, four cTnT isoforms are expressed in a developmentally regulated manner. Expression levels are affected by heart failure. Mutations in the Cardiac Troponin T gene are associated with familial hypertrophic cardiomyopathy and dilated cardiomyopathy. The gene undergoes alternative splicing, producing multiple tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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