Thermo Fisher Scientific LRRTM1 Polyclonal Antibody

Thermo Fisher Scientific LRRTM1 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: RIFQDCRSLK FLDIGYNQLK SLARNSFAGL FKLTELHLEH NDLVKVNFAH
• Storage guidance:
  • Short term: Store at 2–8°C up to 1 week
  • Long term: Store at -20°C in small aliquots to prevent freeze-thaw cycles
• Predicted homology:
  Cow: 100% | Dog: 100% | Guinea Pig: 100% | Horse: 100% | Human: 100% | Mouse: 100% | Rat: 100% | Zebrafish: 86%

Target Information

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation. LRRTM1 and LRRTM2 are most potent at inducing presynaptic differentiation.
Each LRRTM protein is a type I transmembrane protein containing ten extracellular leucine-rich repeats and a short intracellular tail, with distinct developmental expression patterns.
LRRTM1 is a maternally suppressed gene associated paternally with handedness and schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.