Thermo Fisher Scientific Aromatase Polyclonal Antibody
Western blot, IHC, ICC, Flow cytometry에 사용 가능한 Rabbit Polyclonal 항체로, Human Aromatase를 인식합니다. 합성 펩타이드(aa 91-140)를 면역원으로 사용하며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:100 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within Human Aromatase (aa 91–140) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854646 |
Product Specific Information
Positive Control: HepG2, SH-SY-5Y, SK-Br-3, human placenta tissue, mouse cerebellum tissue lysate.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the final steps of estrogen biosynthesis through three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity, indicating that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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