Thermo Fisher Scientific RAB7A Polyclonal Antibody
RAB7A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, Flow cytometry 등에 사용 가능. 높은 특이성과 재현성을 가진 액상 항체로, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Thermo Fisher Scientific RAB7A Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within Human RAB7 amino acids 43–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2854650 |
Product Specific Information
Positive Control: MCF-7, A431, SiHa, rat brain tissue, human tonsil tissue, human liver tissue, human colon cancer tissue, mouse colon tissue.
Target Information
RAB family members are small, RAS-related GTP-binding proteins that are key regulators of vesicular transport. Each RAB protein interacts with multiple effectors involved in exocytic and endocytic pathways.
RAB7A regulates vesicle traffic in late endosomes and lysosomes and is implicated in cellular vacuolation induced by Helicobacter pylori VacA cytotoxin.
Mutations in conserved residues of RAB7A are associated with Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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