Thermo Fisher Scientific RAPSN Monoclonal Antibody (1234)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

View 2 publications 2 publications

Immunohistochemistry (IHC)

-

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

2 µg/mL

View 3 publications 3 publications

Product Specifications

Species Reactivity

Amphibian, Chicken, Fish, Mouse, Rat

Published species

Amphibian, Avian, Chordate, Mouse, Rat, Xenopus

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1234

Immunogen

Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAPSN,uniProtId:P12672-1,ncbiNodeId:10090,antigenRange:1-412,antigenLength:412,antigenImageFileName:MA1-746_RAPSN_P12672-1_House_mouse.svg,antigenImageFileNamePDP:MA1-746_RAPSN_P12672-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2177611

Product Specific Information

MA1-746 detects rapysn from mouse, rat, chicken, amphibian and fish samples.

MA1-746 has been used in immunochemistry procedures using cryosections, immunocytochemistry, immunofluorescence and Western Blot procedures. By Western blot, this antibody detects a 48 kDa protein representing rapsyn from Torpedo californica electrocyte cell extracts.

The MA1-746 immunogen is whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.

Target Information

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.