Thermo Fisher Scientific SND1 Polyclonal Antibody
SND1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에서 WB 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SND1. Recombinant protein control fragment (Product # RP-102051) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789181 |
Product Specific Information
Immunogen sequence:
ARAIKNGKGL HSKKEVPIHR VADISGDTQK AKQFLPFLQR AGRSEAVVEY VFSGSRLKLY LPKETCLITF LLAGIECPRG ARNLPGLVQE GEPFSEEATL FTKEL
Target Information
SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1, and GTF2E2, and forms a ternary complex with Stat6 and POLR2A.
The staphylococcal nuclease-like (SN) domains directly interact with amino acids 1099–1758 of CBP.
SND1/P100 plays an important role in the assembly of the Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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