
Thermo Fisher Scientific AZIN1 Polyclonal Antibody
AZIN1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot과 ELISA에 적합하며, 고순도의 Affinity Chromatography 정제 항체입니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적으로 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 289–448 of human AZIN1 (NP_056962.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2854847 |
Product Specific Information
Immunogen sequence:
AKKVVENDKF PSGVEKTGSD EPAFMYYMND GVYGSFASKL SEDLNTIPEV HKKYKEDEPL FTSSLWGPSC DELDQIVESC LLPELNVGDW LIFDNMGADS FHEPSAFNDF QRPAIYYMMS FSDWYEMQDA GITSDSMMKN FFFVPSCIQL SQEDSFSAEA
Target Information
Antizyme inhibitor (AZIN1) is a protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) such as OAZ1, OAZ2, and OAZ3 on ODC activity by competing with ODC for antizyme binding. It inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of catalytically active ODC homodimers and restoration of polyamine production.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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