
Thermo Fisher Scientific LGR7 Polyclonal Antibody
Thermo Fisher Scientific의 LGR7 Polyclonal Antibody는 인간 LGR7 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 단기 4°C, 장기 -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA528759
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 693–757 of Human GPCR LGR7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546235 |
Product Specific Information
- Recommended positive controls: 293T, H1299
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
LGR7 is a low-density lipoprotein receptor of 757 amino acids belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity. It has seven transmembrane regions, a cysteine-rich motif, 10 LRR domains, and 5 N-glycosylation sites in the N terminus.
Research reports show that LGR7 acts as a receptor for relaxins (RLN1 and RLN2), stimulating adenylate cyclase activation, substrate adhesion, and chemo-migratory capacity of mononuclear leukocytes.
LGR7 is critical for mediating these biological responses via RNA interference lentiviral short hairpin constructs. It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis, and endometrium.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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