Thermo Fisher Scientific D4 Dopamine Receptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human D4 dopamine receptor. Suitable for Western blot and frozen IHC. Provides high specificity with recommended positive control HCT116. Supplied as liquid, unconjugated, 1 mg/mL concentration, stored at 4°C or -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of Human dopamine receptor D4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546232 |
Product Specific Information
- Recommended positive controls: HCT116
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the D4 subtype of the dopamine receptor, a G-protein coupled receptor that inhibits adenylyl cyclase. It is a target for drugs treating schizophrenia and Parkinson’s disease. Mutations in this gene are associated with behavioral phenotypes including autonomic nervous system dysfunction, ADHD, and novelty seeking. The gene contains a polymorphic number (2–10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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