Thermo Fisher Scientific CD97 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD97 protein. Validated for WB, IHC, and ICC applications. Provides strong specificity and sensitivity for research use. Recommended positive controls include A549, HeLa, HepG2, and HCT116 cells.
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- PA528760
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 771–835 of Human CD97 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546236 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes. It is rapidly upregulated on T and B cells upon activation. CD97 exists in alternatively spliced forms, and its cellular ligand is CD55 (DAF), which protects cells from complement-mediated damage. Interaction between CD97 on leukocytes and CD55 on vessel cells facilitates leukocyte activation and migration into tissues. CD97 also plays roles in tumor migration, invasiveness, T cell regulation, and granulocyte homeostasis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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