Thermo Fisher Scientific SUMO-3 Polyclonal Antibody
SUMO-3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 적합. 인간 종 특이적 반응성을 가지며, 항원 친화 크로마토그래피로 정제됨. Alzheimer’s 연구 등 SUMOylation 관련 연구용으로 이상적.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Not specified
- Publications: 1 available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the C-terminal region of the human SUMO-3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533453 |
Target Information
Small ubiquitin-related modifier (SUMO) proteins belong to the ubiquitin-like protein family.
SUMO-3 regulates amyloid beta generation and may play a critical role in the onset or progression of Alzheimer’s disease.
SUMO-2/3 forms poly-SUMO chains, while SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively.
SUMOylation is essential for mammalian cell cycle regulation; SUMO-2/3 localizes to centromeres and condensed chromosomes where it binds CENP-E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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