Thermo Fisher Scientific HOXB7 Polyclonal Antibody
HOXB7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 0.1% sodium azide 포함. 인체 시료에 반응하며 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | View 7 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the C-terminal region of the human HOXB7 (homeobox B7, homeobox C1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533454 |
Target Information
The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis.
The mammalian HOX gene complex consists of 39 genes located on four linkage groups (clusters) across four chromosomes (HOXA, HOXB, HOXC, and HOXD).
HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines.
HOXB7 binds to and transactivates bFGF in melanoma cell lines, while SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes.
HOXB7 may be a key activator of tumor-associated neoangiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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