Thermo Fisher Scientific Calumenin Polyclonal Antibody
Calumenin 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간과 마우스 시료에서 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CALU (Accession O43852), corresponding to amino acid residues L118–D168 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849931 |
Product Specific Information
Antibody detects endogenous levels of total Calumenin.
Target Information
Calumenin is a 315 amino acid Ca²⁺-binding member of the CREC, EF-hand protein family. It is a secreted protein containing six Ca²⁺-binding motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus.
In the presence of Ca²⁺, Calumenin interacts with serum amyloid P component (SAP) and may play a role in immunological defense and amyloidosis. It inhibits the vitamin K-dependent γ-carboxylation system, potentially influencing thrombosis and wound healing through autocrine or paracrine mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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