Thermo Fisher Scientific CaBP8 Polyclonal Antibody
CaBP8 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot과 면역세포염색(ICC/IF)에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며 액상 형태로 제공됩니다. 칼슘 결합 단백질 연구에 활용됩니다.
- 카탈로그번호
- PA5100419
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CALN1 (Accession Q9BXU9), corresponding to amino acid residues M86–L136 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849930 |
Product Specific Information
Antibody detects endogenous levels of total CALN1.
Target Information
Calcium binding proteins (CaBP) play a crucial role in calcium-mediated cellular signal transduction in the central nervous system. The CaBP family shares similarity with calmodulin (CaM I), and CaBP proteins can substitute or augment CaM I function.
CaBP8 contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
CaBP8 and CaBP7 possess a unique targeting mechanism among CaBPs, contributing to differential Ca²⁺-sensing functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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