Thermo Fisher Scientific C1orf77 Polyclonal Antibody
C1orf77 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. 액상 형태로 제공되며, 안정적인 PBS/glycerol 버퍼에 보존됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHTOP (Accession Q9Y3Y2), corresponding to amino acid residues R121–A171 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2849926 |
Product Specific Information
Antibody detects endogenous levels of total C1orf77.
Target Information
CHTOP is a small nuclear protein characterized by an arginine and glycine rich region. It may play an important role in the regulation of fetal globin gene expression and activation of estrogen-responsive genes.
Studies indicate that CHTOP binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), promoting methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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